A short training course enabling delegates to be trained to use the Autism Clinical Interview for Adults (ACIA) - a diagnostic assessment for people age 16+ that can be used in clinical services or research

Delegates will receive training in use and administration, a copy of the manual and ACIA subject and informant booklets

Following training, delegates will be able to use the ACIA in their diagnostic practice and/or research.

Please note that we cannot accept payment via invoice for the training sessions. 

Precision medicine is about going beyond assessing whether a new treatment works on average to predicting which subgroups of patients receive benefit and to what extent. When subgroups, often defined by biomarkers, genetic, phenotypic or psychosocial characteristics, are associated with a treatment’s efficacy or toxicity, precision medicine offers substantial advantages to patients, trial sponsors, and the wider healthcare system. However, a barrier to realising the promise of precision medicine is the inappropriate use of traditional clinical trial design and analysis, which rely on estimates of population-averaged effects.

In this course we introduce the concept of precision medicine and cover innovative approaches. This includes novel designs (biomarker-guided, basket, umbrella, adaptive signature, adaptive enrichment designs and Sequential Multiple Assignment Randomized Trials) as well as efficient analysis approaches (e.g. Bayesian hierarchical modelling, identifying patient subgroups using high-dimensional genetic data) to help estimate sub-group specific treatment effects. These approaches have all been developed to improve the power, quality of information, and patient benefit provided by clinical trials. Examples from a wide variety of therapeutic areas will be discussed, with implementation in R software. Perspectives will be given on the future development of design, conduct and analysis of clinical trials in the field.

Course tutors:
Dr Svetlana Cherlin, Newcastle University
Professor James Wason, Newcastle University
Dr Haiyan Zheng, University of Bath